Webinar
Building a Better Prefilled Syringe for Vaccines
This on-demand webinar examines the technical, regulatory, and supply chain challenges of transitioning vaccine packaging from vials to prefilled syringes — covering plunger compound selection and extractables performance at ultra-low temperatures, container closure integrity (CCI) at -50°C, rigid needle shield compatibility, and how Datwyler's global production footprint supports vaccine supply chain resilience.
Status
Published
Format
Webinar
Language
English
Access
Registration Required
Resource Overview
About this Webinar
Prefilled syringes offer meaningful advantages for vaccine delivery — improved dose accuracy, reduced healthcare worker error risk, and compatibility with auto-injector platforms — yet transitioning from vials introduces significant technical challenges around material compatibility, ultra-low temperature container closure integrity (CCI), and global supply availability that demand careful packaging component engineering. This on-demand webinar, presented by Datwyler's Global Platform Leader for Prefilled Syringes and Cartridges, walks pharmaceutical packaging and formulation teams through the key decisions in building a high-performance prefilled syringe for vaccine applications. Topics include comparative extractables profiling of FM257, FM457, and NeoFlex™ plungers via HS-GC/MS volatile organic compound analysis; CCI and gliding force performance at -50°C for mRNA and other cold-chain vaccines, accounting for differential thermal expansion between rubber, borosilicate glass, and plastic materials; the importance of early engagement with barrel manufacturers and system suppliers to optimize rigid needle shield (RNS) pull-off forces for fill-finish processability; DMF support in the US, Canada, and China markets; and how RTU components eliminate sterilization capital investment and camera-inspected products reduce filled syringe rejection rates. The webinar also addresses real-world peak demand scenarios from COVID-19 vaccine rollout and Datwyler's ongoing FirstLine® capacity expansion in India and Belgium.
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